L759633
Cat. No.：YN322333
| 产品名称: | L759633 |
| CAS No.: | 174627-50-0 |
| Chemical Name: | 3-(1,1-dimethylheptyl)-6aR,7,10,10aR-tetrahydro-1-methoxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran |
| Synonyms: | L-759,633; L 759,633; L759633. |
| 分子量: | 384.6 |
| 分子式: | C26H40O2 |
| SMILES: | CCCCCCC(C)(C)c1cc(OC)c2c(c1)OC(C)(C)C1CC=C(C)C[C@@H]21 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | L759633 是一种有效和选择性的大麻素受体 2CB2受体激动剂，对CB2和CB1的Ki值分别为 6.4 nM 和 1043 nM。L759633 可以抑制 Forskolin 刺激的 cAMP 产生。 |
| IC50和靶点: | [{name:"CB2:6.4 nM (Ki)"},{name: "CB1:1043 nM (Ki)"}] |
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| Solvent & Solubility: |
Ross, R.A., Brockie, H.C., Stevenson, L.A., et al.Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656 and AM630Br. J. Pharmacol.126(3),665-672(1999)
