GW-405833
Cat. No.：YN322346
CAS No. ：180002-83-9
| 产品名称: | GW-405833 |
| CAS No.: | 180002-83-9 |
| Chemical Name: | (2,3-dichlorophenyl)[5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1H-indol-1-yl]-methanone |
| Synonyms: | L768242 |
| 分子量: | 447.4 |
| 分子式: | C23H24Cl2N2O3 |
| SMILES: | COC1=CC=C(N(C(C2=C(Cl)C(Cl)=CC=C2)=O)C(C)=C3CCN4CCOCC4)C3=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GW-405833 (L768242) 是一种有效的、选择性的大麻素受体2 (CB2) 激动剂，EC50值为 50.7 nM。GW-405833 也表现为非竞争性的CB1拮抗剂。GW-405833 抑制炎症性和神经性疼痛。 |
| IC50和靶点: | [{name:"CB2:50.7 nM (EC50)"},{name: "CB1:16.1 μM (EC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Guindon, J., and Hohmann, A.G.Cannabinoid CB2 receptors: A therapeutic target for the treatment of inflammatory and neuropathic painBr. J. Pharmacol.153(2),319-334(2008)
