DS-1205b free base
Cat. No.：YN380358
CAS No. ：1855860-24-0
| 产品名称: | DS-1205b free base |
| CAS No.: | 1855860-24-0 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 284.323 |
| 分子式: | C14H16N6O |
| SMILES: | O=C(C1=CN(CC2CCOCC2)C=C(C3=NC=C(C)C=C3)C1=O)NC4=CC=C(C5=CC(C6=CC=C(OC[C@@H]7OCCOC7)C(OC)=C6)=CN=C5N)C(F)=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | DS-1205b free base 是一种有效和选择性的AXL激酶抑制剂，IC50值为 1.3 nM。DS-1205b free base 还可以抑制MER，MET和TRKA，IC50值分别为 63、104 和 407 nM。 DS-1205b free base 可以抑制细胞迁移和肿瘤生长。 |
| IC50和靶点: | [{name:"AXL:1.3 nM (IC50)"},{name: "MER:63 nM (IC50)"},{name: "TrkA:407 nM (IC50)"},{name: "Met:104 nM (IC50)"}] |
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| Solvent & Solubility: |
