PF-06733804
Cat. No.：YN380360
| 产品名称: | PF-06733804 |
| CAS No.: | 1873373-33-1 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 474.38 |
| 分子式: | C20H19F5N4O4 |
| SMILES: | NC1=C(O[C@H]2CN(CC2(F)F)C(CC2=CC=C(OC(F)(F)F)C=C2)=O)C=C(C(=O)NC)C=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-06733804 是一种有效的pan-Trk抑制剂，抑制TrkA，TrkB和TrkC细胞，IC50分别为 8.4 nM，6.2 nM 和 2.2 nM。具有抗痛觉过敏作用。 |
| IC50和靶点: | [{name:"TrkA:8.4 nM (IC50, in cell-based assays)"},{name: "TrkB:6.2 nM (IC50, in cell-based assays)"},{name: "TrkC:2.2 nM (IC50, in cell-based assays)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
