AM-6494
Cat. No.：YN380361
| 产品名称: | AM-6494 |
| CAS No.: | 1874232-80-0 |
| Chemical Name: | |
| Synonyms: | N-(3-((1S,5S,6S)-3-Amino-1-(methoxymethyl)-5-methyl-2-thia-4-azabicyclo[4.1.0]hept-3-en-5-yl)-4,5-difluorophenyl)-5-(prop-2-yn-1-yloxy)pyrazine-2-carboxamide;N-{3-[(1S,5S,6S)-3-amino-1-(methoxymethyl)-5-methyl-2-thia-4-azabicyclo[4.1.0]hept-3-en-5-yl]-4,5 |
| 分子量: | 473.4957 |
| 分子式: | C22H21F2N5O3S |
| SMILES: | S1C(N([H])[H])=N[C@@](C2=C(C(=C([H])C(=C2[H])N([H])C(C2=C([H])N=C(C([H])=N2)OC([H])([H])C#C[H])=O)F)F)(C([H])([H])[H])[C@]2([H])C([H])([H])[C@]12C([H])([H])OC([H])([H])[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AM-6494 是一种有效的口服 β-位点淀粉样前体蛋白裂解酶 1(BACE1)抑制剂 (IC50=0.4 nM)，体内选择性高于BACE2(IC50=18.6 nM)。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
