NGB 2904
Cat. No.:YN322359
CAS No. :189060-98-8
产品名称: | NGB 2904 |
CAS No.: | 189060-98-8 |
Chemical Name: | N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide |
Synonyms: | NGB2904; NGB 2904; NGB-2904. |
分子量: | 494.46 |
分子式: | C28H29Cl2N3O |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | NGB 2904 是一种有效,选择性,具有口服活性和可透过血脑屏障的多巴胺D3受体的拮抗剂,Ki值为 1.4 nM。NGB 2904 对 D3 的选择性高于 D2,5-HT2,α1,D4,D1 和 D5 受体 (Ki=217,223,642,>5000,>10000 和 >10000 nM)。NGB 2904 可拮抗 Quinpirole 刺激的有丝分裂。 |
IC50和靶点: | [{name:"D3 Receptor:1.4 nM (Ki)"}] |
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