4-DAMP
Cat. No.：YN322369
CAS No. ：1952-15-4
| 产品名称: | 4-DAMP |
| CAS No.: | 1952-15-4 |
| Chemical Name: | 4-[(2,2-diphenylacetyl)oxy]-1,1-dimethyl-piperidinium, monoiodide |
| Synonyms: | 4-DAMP methiodide |
| 分子量: | 451.3 |
| 分子式: | C21H26NO2 • I |
| SMILES: | O=C(OC1CC[N+](C)(C)CC1)C(C2=CC=CC=C2)C3=CC=CC=C3.[I-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 4-DAMP 是M3 受体的有效拮抗剂，并且对密切相关的M5 受体也有很高的亲和力。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
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Watson, N., Daniels, D.V., Ford, A.P.D.W., et al.Comparative pharmacology of recombinant human M3 and M5 muscarinic receptors expressed in CHO-K1 cellsBr. J. Pharmacol.127(2),590-596(1999)
Joo, M.C., Kim, Y.S., Choi, E.S., et al.Changes in the muscarinic receptors on the colonic smooth muscles of rats with spinal cord injuryAnn.Rehabil.Med.35(5),589-598(2011)
Lee, B.H., Gauna, A.E., Perez, G., et al.Autoantibodies against muscarinic type 3 receptor in Sjögren's syndrome inhibit aquaporin 5 traffickingPLoS One8(1),(2013)
