CRT0273750
Cat. No.:YN322375
CAS No. :1979939-16-6
产品名称: | CRT0273750 |
CAS No.: | 1979939-16-6 |
Chemical Name: | N-[(1S)-1-(4-chlorophenyl)ethyl]-3-[[4-(trifluoromethoxy)phenyl]methyl]-3H-imidazo[4,5-b]pyridine-2-propanamide |
Synonyms: | |
分子量: | 502.9 |
分子式: | C25H22ClF3N4O2 |
SMILES: | O=C(N[C@@H](C)C1=CC=C(Cl)C=C1)CCC2=NC3=CC=CN=C3N2CC4=CC=C(OC(F)(F)F)C=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CRT0273750 是 ATX 抑制剂的先导化合物,并调节血浆中 LPA 水平。CRT0273750 可用于 ATX/LPA 依赖性癌症模型。 |
IC50和靶点: | |
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Shah, P., A., C., Foxton, C., et al.Discovery of potent inhibitors of the lysophospholipase autotaxinBioorg. Med. Chem. Lett.26(22),5403-5410(2016)