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Tranylcypromine hydrochloride (GMP)

Cat. No.:YN380365

  • CAS No. :1986-47-6

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    • 参考文献
    • 产品名称: Tranylcypromine hydrochloride (GMP)
      CAS No.: 1986-47-6
      Chemical Name: (1R,2S)-rel-2-phenyl-cyclopropanamine, monohydrochloride
      Synonyms:SKF 385 hydrochloride (GMP
      分子量:169.7
      分子式:C9H11N • HCl
      SMILES:N[C@@H]1CC1c1ccccc1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Tranylcypromine (SKF 385) hydrochloride (GMP) 是Tranylcypromine(HY-17447) GMP 级别的小分子,可适用于细胞疗法中的辅助试剂。Tranylcypromine hydrochloride 是一种有效的单胺氧化酶抑制剂。
      IC50和靶点:
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    • Schmidt, D.M.Z., and McCafferty, D.G.trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1Biochemistry46,4408-4416(2007)

      Lee, M.G., Wynder, C., Schidt, D.M., et al.Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medicationsChem. Biol.13(6),563-567(2006)

      Zhou, H., Li, W., Zhu, S., et al.Conversion of mouse epiblast stem cells to an earlier pluripotency state by small moleculesJ. Biol. Chem.285(39),29676-29680(2010)

      Sun, G., Alzayady, K., Stewart, R., et al.Histone demethylase LSD1 regulates neural stem cell proliferationMol. Cell. Biol.30(8),1997-2005(2010)

      Reed, A.L., Happe, H.K., Petty, F., et al.Juvenile rats in the forced-swim test model the human response to antidepressant treatment for pediatric depressionPsychopharmacology (Berl.)197(3),433-441(2008)

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