Tranylcypromine hydrochloride (GMP)
Cat. No.:YN380365
产品名称: | Tranylcypromine hydrochloride (GMP) |
CAS No.: | 1986-47-6 |
Chemical Name: | (1R,2S)-rel-2-phenyl-cyclopropanamine, monohydrochloride |
Synonyms: | SKF 385 hydrochloride (GMP |
分子量: | 169.7 |
分子式: | C9H11N • HCl |
SMILES: | N[C@@H]1CC1c1ccccc1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Tranylcypromine (SKF 385) hydrochloride (GMP) 是Tranylcypromine(HY-17447) GMP 级别的小分子,可适用于细胞疗法中的辅助试剂。Tranylcypromine hydrochloride 是一种有效的单胺氧化酶抑制剂。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Schmidt, D.M.Z., and McCafferty, D.G.trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1Biochemistry46,4408-4416(2007)
Lee, M.G., Wynder, C., Schidt, D.M., et al.Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medicationsChem. Biol.13(6),563-567(2006)
Zhou, H., Li, W., Zhu, S., et al.Conversion of mouse epiblast stem cells to an earlier pluripotency state by small moleculesJ. Biol. Chem.285(39),29676-29680(2010)
Sun, G., Alzayady, K., Stewart, R., et al.Histone demethylase LSD1 regulates neural stem cell proliferationMol. Cell. Biol.30(8),1997-2005(2010)
Reed, A.L., Happe, H.K., Petty, F., et al.Juvenile rats in the forced-swim test model the human response to antidepressant treatment for pediatric depressionPsychopharmacology (Berl.)197(3),433-441(2008)