CP-465022
Cat. No.：YN380366
CAS No. ：199655-36-2
| 产品名称: | CP-465022 |
| CAS No.: | 199655-36-2 |
| Chemical Name: | 3-(2-Chlorophenyl)-2-[2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-4(3H)-quinazolinone; |
| Synonyms: | |
| 分子量: | 462.95 |
| 分子式: | C26H24ClFN4O |
| SMILES: | CCN(CC)CC1=CC=CC(=N1)/C=C/C2=NC3=C(C=C(C=C3)F)C(=O)N2C4=CC=CC=C4Cl.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CP-465022 是一种强效的、选择性的、非竞争性的AMPA受体拮抗剂，具有抗惊厥活性。CP-465022 对 Kainate 诱导反应具有抑制作用，IC50为 25 nM。CP-465022 是研究 AMPA 受体在生理和病理方面研究的有效工具。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Maher, M. P., et al.: J. Pharmacol. Exp. Ther., 357, 394-414 (2016)
Yelshanskaya, M. V., et al.: Neuron, 91, 1305-1315 (2016)
