Fustin
Cat. No.：YN380369
| 产品名称: | Fustin |
| CAS No.: | 20725-03-5 |
| Chemical Name: | (2R,3R)-rel-2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,7-dihydroxy-4H-1-benzopyran-4-one |
| Synonyms: | |
| 分子量: | 288.25218 |
| 分子式: | C15H12O6 |
| SMILES: | OC(C=CC([C@H]1OC2=CC(O)=CC=C2C([C@@H]1O)=O)=C3)=C3O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) 是一种有效的淀粉样 β (Aβ) 抑制剂。Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) 可增加 Aβ (1-42) 诱导的乙酰胆碱 (ACh) 水平、胆碱乙酰转移酶 (ChAT) 活性和 ChAT 基因的表达。Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) 降低 Aβ (1 |
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Marín, L., Gutiérrez-Del-Río, I., Villar, C.J., et al.De novo biosynthesis of garbanzol and fustin in Streptomyces albus based on a potential flavanone 3-hydroxylase with 2-hydroxylase side activityMicrob. Biotechnol.14(5),2009-2024(2021)
Kumazoe, M., Fujimura, Y., Yoshitomi, R., et al.Fustin, a flavanonol, synergically potentiates the anticancer effect of green tea catechin epigallocatechin-3-O-gallate with activation of the eNOS/cGMP axisJ. Agric. Food Chem.70(11),3458-3466(2022)
Gilani, S.J., Bin-Jumah, M.N., Al-Abbasi, F.A., et al.Fustin ameliorates hyperglycemia in streptozotocin induced type-2 diabetes via modulating glutathione/superoxide dismutase/catalase expressions, suppress lipid peroxidation and regulates histopathological changesSaudi J. Biol. Sci.28(12),6963-6971(2021)
Jin, C.-H., Shin, E.-J., Park, J.-B., et al.Fustin flavonoid attenuates β-amyloid (1-42)-induced learning impairmentJ. Neurosci. Res.87(16),3658-3670(2009)
