PXS-5120A
Cat. No.：YN380371
| 产品名称: | PXS-5120A |
| CAS No.: | 2125955-70-4 |
| Chemical Name: | |
| Synonyms: | 1H-Indole-5-carboxylic acid, 1-[(2Z)-4-amino-2-fluoro-2-buten-1-yl]-3-[3-[(dimethylamino)sulfonyl]phenyl]-2-methyl-, hydrochloride |
| 分子量: | 481.97 |
| 分子式: | C22H25ClFN3O4S |
| SMILES: | C1(=C(C)N(C/C(=C/CN)/F)C2C=CC(=CC1=2)C(O)=O)C1C=CC=C(S(=O)(N(C)C)=O)C=1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PXS-5120A 是一种有效的，不可逆的Lysyl Oxidase-like 2/3 (LOXL2/3)的氟代烯丙胺抑制剂，具有抗纤维化活性。与LOXL(pIC50为 5.8) 相比，PXS-5120A 对LOXL2(Ki为 83 nM;pIC50为 8.4) 的选择性高 300 倍以上。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
