PXS-5153A
Cat. No.：YN380372
| 产品名称: | PXS-5153A |
| CAS No.: | 2125956-82-1 |
| Chemical Name: | |
| Synonyms: | PXS5153A;PXS 5153A |
| 分子量: | 438.95 |
| 分子式: | C20H24ClFN4O2S |
| SMILES: | C(S(N(C)C)(=O)=O)1=CC=CC(C2C3=NC=CC=C3N(C/C(/F)=C/CN)C=2C)=C1.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PXS-5153A 是一种有效的、选择性的、具有口服活性和快速起效的赖氨酰氧化酶 2/3(LOXL2/LOXL3)的双抑制剂，对几乎所有哺乳动物LOXL2的IC50均< 40 nM，对人类LOXL3 的IC50为63 nM。PXS-5153A 可减少交联，改善纤维化。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Findlay, Alison D., et al.:From PCT Int. Appl. (2017), WO 2017136870 A1 20170817
