GLPG2938
Cat. No.:YN322390
CAS No. :2130996-00-6
产品名称: | GLPG2938 |
CAS No.: | 2130996-00-6 |
Chemical Name: | N-[2-ethoxy-6-(trifluoromethyl)-4-pyridinyl]-N′-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-3-pyridazinyl]methyl]-urea |
Synonyms: | |
分子量: | 503.4012592 |
分子式: | C20H19F6N7O2 |
SMILES: | O=C(NCC1=CC(C)=C(C2=CN(C)N=C2C(F)(F)F)N=N1)NC3=CC(C(F)(F)F)=NC(OCC)=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | GLPG2938 是一种有效和选择性S1P2拮抗剂。GLPG2938 可用于特发性肺纤维化的研究。 |
IC50和靶点: | |
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Mammoliti, O., Palisse, A., Joannesse, C., et al.Discovery of the S1P2 antagonist GLPG2938 (1-[2-ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a preclinical candidate for the treatment of idiopathic pulmonary fibrosisJ. Med. Chem.64(9),6037-6058(2021)