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GLPG2938

Cat. No.:YN322390

  • CAS No. :2130996-00-6

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    • 参考文献
    • 产品名称: GLPG2938
      CAS No.: 2130996-00-6
      Chemical Name: N-[2-ethoxy-6-(trifluoromethyl)-4-pyridinyl]-N′-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-3-pyridazinyl]methyl]-urea
      Synonyms:
      分子量:503.4012592
      分子式:C20H19F6N7O2
      SMILES:O=C(NCC1=CC(C)=C(C2=CN(C)N=C2C(F)(F)F)N=N1)NC3=CC(C(F)(F)F)=NC(OCC)=C3
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: GLPG2938 是一种有效和选择性S1P2拮抗剂。GLPG2938 可用于特发性肺纤维化的研究。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Mammoliti, O., Palisse, A., Joannesse, C., et al.Discovery of the S1P2 antagonist GLPG2938 (1-[2-ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a preclinical candidate for the treatment of idiopathic pulmonary fibrosisJ. Med. Chem.64(9),6037-6058(2021)

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