PF-04634817 succinate
Cat. No.：YN322392
| 产品名称: | PF-04634817 succinate |
| CAS No.: | 2140301-98-8 |
| Chemical Name: | |
| Synonyms: | PF 4634817 succinate |
| 分子量: | 629.67 |
| 分子式: | C29H42F3N5O7 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-0463481 succinate 是一种有效的具有口服活性的双效CCR2/CCR5拮抗剂，对人和啮齿类动物的CCR2效价相当 (ratIC50=20.8 nM)，对CCR2的效价是CCR5的 10-20 倍 (ratIC50=470 nM)。PF-0463481 succinate 安全、耐受性好，有潜力用于研究糖尿病肾病。 |
| IC50和靶点: | [{name:"Rat CCR2:20.8 nM (IC50)"},{name: "CCR5:470 nM (IC50)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
