Histrelin acetate
Cat. No.：YN322399
| 产品名称: | Histrelin acetate |
| CAS No.: | 220810-26-4 |
| Chemical Name: | 6-[1-(phenylmethyl)-D-histidine]-9-(N-ethyl-L-prolinamide)-1-9-luteinizing hormone-releasing factor (swine), acetate |
| Synonyms: | 醋酸组氨瑞林 |
| 分子量: | 1323.5 |
| 分子式: | C66H86N18O12 • XC2H4O2 |
| SMILES: | O=C([C@@H]1CCC(N1)=O)N[C@@H](CC2=CNC=N2)C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N[C@@H](CO)C(N[C@@H](CC5=CC=C(O)C=C5)C(N[C@H](CC6=CN(CC7=CC=CC=C7)C=N6)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N8CCC[C@H]8C(NCC)=O)=O)=O)=O)=O)=O)=O)=O.OC(C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Histrelin acetate，一种 GnRH 类似物，是一种GnRH受体激动剂。Histrelin acetate 可增加血清中促黄体激素(LH)、促卵泡激素 (FSH) 和睾酮水平。Histrelin acetate 可用于前列腺癌、子宫内膜异位症的研究。 |
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Nederpelt, I., Georgi, V., Schiele, F., et al.Characterization of 12 GnRH peptide agonists - a kinetic perspectiveBr. J. Pharmacol.173(1),128-141(2016)
Juszczak, M., and Boczek-Leszczyk, E.Hypothalamic gonadotropin-releasing hormone receptor activation stimulates oxytocin release from the rat hypothalamo-neurohypophysial system while melatonin inhibits this processBrain Res. Bull.81(1),185-190(2010)
Boczek-Leszczyk, E., Stempniak, B., and Juszczak, M.Vasopressin release from the rat hypothalamo-neurohypophysial system: Effects of gonadotrophin-releasing hormone (GnRH), its analogues and melatoninJ. Physiol. Pharmacol.61(4),459-466(2010)
Sundaram, K., Thau, R.B., Goldstein, M., et al.Effect of an LHRH agonist on pituitary and testicular function in rhesus monkeysJ. Reprod. Fertil.72(2),365-371(1984)
