JHU37160
Cat. No.：YN322418
CAS No. ：2369979-68-8
| 产品名称: | JHU37160 |
| CAS No.: | 2369979-68-8 |
| Chemical Name: | |
| Synonyms: | JHU37160 (DREADD ligand);JHU37160;s9790 |
| 分子量: | 358.84 |
| 分子式: | C19H20ClFN4 |
| SMILES: | CCN1CCN(CC1)C2=NC3=CC(=CC=C3NC4=C2C=CC=C4F)Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JHU37160 是一种有效和可透过血脑屏障的DREADD激动剂，对hM3Dq和hM4Di DREADDs的EC50值分别为 18.5 nM 和 0.2 nM。JHU37160 在小鼠脑组织中表现出来自 DREADDs 的选择性 [3H]Clozapine 置换作用，而不来自其他 Clozapine 结合部位。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
