AL-8810
Cat. No.：YN322427
| 产品名称: | AL-8810 |
| CAS No.: | 246246-19-5 |
| Chemical Name: | 9α,15R-dihydroxy-11β-fluoro-15-(2,3-dihydro-1H-inden-2-yl)-16,17,18,19,20-pentanor-prosta-5Z,13E-dien-1-oic acid |
| Synonyms: | AL-8810, AL8810, AL 8810 |
| 分子量: | 402.5 |
| 分子式: | C24H31O4F |
| SMILES: | O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@H](O)C2CC3=CC=CC=C3C2)[C@@H](F)C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AL-8810 是 PGF2α的一种 11β- 氟类似物，是PGF2α受体(FP 受体) 的有效和选择性拮抗剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Griffen, B.W., Klimko, P., Crider, J.Y., et al.AL-8810: A novel prostaglandin F2α analog with selective antagonist effects at the prostaglandin F2α (FP) receptorJ. Pharmacol. Exp. Ther.290(3),1278-1284(1999)
Sharif, N.A., Williams, G.W., and Kelly, C.R.Bimatoprost and its free acid are prostaglandin FP receptor agonistsEur. J. Pharmacol.432,211-213(2001)
Sharif, N.A., Kelly, C.R., and Crider, J.Y.Agonist activity of Bimatoprost, Travoprost, Latanoprost, Unoprostone isopropyl ester and other prostaglandin analogs at the cloned human ciliary body FP prostaglandin receptorJ. Ocul. Pharmacol. Ther.18,313-324(2002)
