SB-328437
Cat. No.：YN322429
CAS No. ：247580-43-4
| 产品名称: | SB-328437 |
| CAS No.: | 247580-43-4 |
| Chemical Name: | N-(1-naphthalenylcarbonyl)-4-nitro-L-phenylalanine, methyl ester |
| Synonyms: | (S)-METHYL-2-NAPHTHOYLAMINO-3-(4-NITROPHENYL)PROPIONATE;methyl (2S)-2-(naphthalene-1-carbonylamino)-3-(4-nitrophenyl)propanoate;SB 328437;N-(1-Naphthalenylcarbonyl)-4-nitro-L-phenylalanineMethylester;L-Phenylalanine, N-(1-naphthalenylcarbonyl)-4-nitro-, m |
| 分子量: | 378.3781 |
| 分子式: | C21H18N2O5 |
| SMILES: | O=C(N[C@@H](CC1=CC=C([N+]([O-])=O)C=C1)C(OC)=O)C2=C(C=CC=C3)C3=CC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SB-328437 是一种有效的、选择性的非肽类CCR3拮抗剂，其IC50为 4.5 nM。 |
| IC50和靶点: | [{name:"CCR3:4.5 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
White, J.R., Lee, J.M., Dede, K., et al.Identification of potent, selective non-peptide CC chemokine receptor-3 antagonist that inhibits eotaxin-, eotaxin-2-, and monocyte chemotactic protein-4-induced eosinophil migrationJ. Biol. Chem.275(47),36626-36631(2000)
Wang, T., Zhang, J.-Y., Wang, X.-D., et al.Effects of CCR3(chemokine receptor-3) on Muc5ac in airway of asthmatic miceZhongguo Mianyixue Zazhi31(8),1019-1023(2015)
