MS 245 oxalate
Cat. No.:YN322444
产品名称: | MS 245 oxalate |
CAS No.: | 275363-58-1 |
Chemical Name: | 5-methoxy-N,N-dimethyl-1-(phenylsulfonyl)-1H-indole-3-ethanamine, monoethanedioate |
Synonyms: | |
分子量: | 448.5 |
分子式: | C19H22N2O3S • C2H2O4 |
SMILES: | COC1=CC=C(N(S(C2=CC=CC=C2)(=O)=O)C=C3CCN(C)C)C3=C1.OC(C(O)=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MS 245 oxalate 是一种有效的5-HT6受体拮抗剂,Ki为 2 nM。 |
IC50和靶点: | |
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Tsai, Y., Dukat, M., Slassi, A., et al.N1-(Benzenesulfonyl)tryptamines as novel 5-HT6 antagonistsBioorg. Med. Chem. Lett.10(20),2295-2299(2000)
Pullagurla, M., Bondareva, T., Young, R., et al.Modulation of the stimulus effects of (+)amphetamine by the 5-HT6 antagonist MS-245Pharmacol. Biochem. Behav.78(2),263-268(2004)
Young, R., Bondareva, T., Wesolowska, A., et al.Effect of the 5-HT6 serotonin antagonist MS-245 on the actions of (−)nicotinePharmacol. Biochem. Behav.85(1),170-177(2006)