TDI-10229
Cat. No.：YN322448
CAS No. ：2810887-45-5
| 产品名称: | TDI-10229 |
| CAS No.: | 2810887-45-5 |
| Chemical Name: | 4-chloro-6-[1,5-dimethyl-4-(phenylmethyl)-1H-pyrazol-3-yl]-2-pyrimidinamine |
| Synonyms: | |
| 分子量: | 313.78464 |
| 分子式: | C16H16ClN5 |
| SMILES: | NC1=NC(Cl)=CC(C2=NN(C)C(C)=C2CC3=CC=CC=C3)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TDI-10229 是一种口服有效的可溶性腺苷酸环化酶(sAC, ADCY10)抑制剂 (IC50值为 195 nM)。TDI-10229 在生化和细胞分析中都显示出对 sAC 的纳摩尔级抑制，并表现出足以保证其用作体内工具化合物的小鼠药代动力学特性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Balbach, M., Ghanem, L., Rossetti, T., et al.Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilizationMol. Hum. Reprod.27(9),gaab054(2021)
