GLP-1R agonist 2
Cat. No.：YN322449
| 产品名称: | GLP-1R agonist 2 |
| CAS No.: | 281209-71-0 |
| Chemical Name: | 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-2-quinoxalinamine |
| Synonyms: | |
| 分子量: | 348.24862 |
| 分子式: | C13H15Cl2N3O2S |
| SMILES: | ClC1=C(Cl)C=C(N=C(NC(C)(C)C)C(S(C)(=O)=O)=N2)C2=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GLP-1R agonist 2 (compound 2) 是一种有效的GLP-1R激动剂。GLP-1R agonist 2 具有研究 2 型糖尿病和肥胖等代谢性疾病的潜力。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Koole, C., Wootten, D., Simms, J., et al.Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: Implications for drug screeningMol. Pharmacol.78(3),456-465(2010)
Knudsen, L.B., Kiel, D., Teng, M., et al.Small-molecule agonists for the glucagon-like peptide 1 receptorProc. Natl. Acad. Sci. USA104(3),937-942(2007)
Irwin, N., Flatt, P.R., Patterson, S., et al.Insulin-releasing and metabolic effects of small molecule GLP-1 receptor agonist 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxalineEur. J. Pharmacol.628(1-3),268-273(2010)
