Org41841
Cat. No.:YN322455
产品名称: | Org41841 |
CAS No.: | 301847-37-0 |
Chemical Name: | 5-amino-N-(1,1-dimethylethyl)-4-(3-methoxyphenyl)-2-(methylthio)-thieno[2,3-d]pyrimidine-6-carboxamide |
Synonyms: | |
分子量: | 402.53574 |
分子式: | C19H22N4O2S2 |
SMILES: | O=C(C1=C(N)C2=C(C3=CC(OC)=CC=C3)N=C(SC)N=C2S1)NC(C)(C)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ORG41841 是促黄体激素/绒毛膜促性腺激素受体 (LHCGR) 和促甲状腺激素受体 (TSHR) 的部分激动剂,其EC50值分别为 0.2 和 7.7 μM。 |
IC50和靶点: | |
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Clinical Trial: | |
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Moore, A., Jaeschke, H., Kleinau, G., et al.Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: Structure-activity relationships and selective binding patternsJ. Med. Chem.49(13),3888-3896(2006)