Ro 01-6128
Cat. No.：YN322456
CAS No. ：302841-86-7
| 产品名称: | Ro 01-6128 |
| CAS No.: | 302841-86-7 |
| Chemical Name: | N-(2,2-diphenylacetyl)-carbamic acid, ethyl ester |
| Synonyms: | |
| 分子量: | 283.3 |
| 分子式: | C17H17NO3 |
| SMILES: | O=C(NC(OCC)=O)C(C1=CC=CC=C1)C2=CC=CC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ro 01-6128 是mGluR1的一种正向变构调节剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Sheffler, D.J., and Conn, P.J.Allosteric potentiators of metabotropic glutamate receptor subtype 1a differentially modulate independent signaling pathways in baby hamster kidney cellsNeuropharmacology55(4),419-427(2008)
Knoflach, F., Mutel, V., Jolidon, S., et al.Positive allosteric modulators of metabotropic glutamate 1 receptor: Characterization, mechanism of action, and binding siteProc. Natl. Acad. Sci. USA98(23),13402-13407(2001)
Hemstapat, K., de Paulis, T., Chen, Y., et al.A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulatorsMol. Pharmacol.70(2),616-626(2006)
