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1-Oleoyl lysophosphatidic acid sodium

Cat. No.:YN322471

  • CAS No. :325465-93-8

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: 1-Oleoyl lysophosphatidic acid sodium
      CAS No.: 325465-93-8
      Chemical Name: 9Z-octadecenoic acid, (2R)-2-hydroxy-3-(phosphonooxy)propyl ester, monosodium salt
      Synonyms:1-Oleoyl-sn-glycero-3-phosphate sodium; 1-Oleoyl-LPA sodium
      分子量:458.5
      分子式:C21H40O7P • Na
      SMILES:CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](O)COP([O-])(O)=O)=O.[Na+]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) sodium 是一种有效的生物活性磷脂,是一种LPA受体激活剂。1-Oleoyl lysophosphatidic acid sodium 可通过诱导 DNA 合成促进有丝分裂。1-Oleoyl lysophosphatidic acid sodium 也参与正常和病理性情绪反应,包括焦虑和抑郁。
      IC50和靶点:
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      In Vivo:
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    • Moolenaar, W.H.LPA: A novel lipid mediator with diverse biological actionsTrends Cell Biol.4(6),213-219(1994)

      Noguchi, K., Ishii, S., and Shimizu, T.Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg familyJ. Biol. Chem.278(28),25600-25606(2003)

      Jalink, K., Hengeveld, T., Mulder, S., et al.Lysophosphatidic acid-induced Ca2+ mobilization in human A4431 cells: Structure-activity analysisBiochem. J.307,609-616(1995)

      van Corven, E.J., van Rijswijk, A., Jalink, K., et al.Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suraminBiochem. J.281,163-169(1992)

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