Picotamide
Cat. No.：YN322473
| 产品名称: | Picotamide |
| CAS No.: | 32828-81-2 |
| Chemical Name: | 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide |
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| 分子量: | 376.4 |
| 分子式: | C21H20N4O3 |
| SMILES: | O=C(C1=CC=C(OC)C(C(NCC2=CC=CN=C2)=O)=C1)NCC3=CN=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Picotamide 是一种血栓素 A2 (TxA2)合成酶和受体的联合抑制剂。Picotamide 具有抗血小板活性。Picotamide 在糖尿病中促进微量白蛋白尿的减少和颈动脉斑块的生长抑制。Picotamide 可用于急性或慢性心血管疾病的研究。 |
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Celestini, A., and Violi, F.A review of picotamide in the reduction of cardiovascular events in diabetic patientsVasc. Health Risk Manag.3(1),93-98(2008)
Modesti, P.A., Cecioni, I., Colella, A., et al.Binding kinetics and antiplatelet activities of picotamide, a thromboxane A2 receptor antagonistBr. J. Pharmacol.112(1),81-86(1994)
Matera, G., Chisari, M., Altavilla, D., et al.Selective thromboxane synthetase inhibition by picotamide and effects on endotoxin-induced lethalityProc. Soc. Exp. Biol. Med.187(1),58-61(1988)
