BQCA
Cat. No.：YN322478
CAS No. ：338747-41-4
| 产品名称: | BQCA |
| CAS No.: | 338747-41-4 |
| Chemical Name: | 1,4-dihydro-1-[(4-methoxyphenyl)methyl]-4-oxo-3-quinolinecarboxylic acid |
| Synonyms: | 1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;BQCA;1-[(4-methoxyphenyl)methyl]-4-oxoquinoline-3-carboxylic acid;1-(4-methoxybenzyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid;AC1LRSH3;CHEMBL608112;CTK8F8329;Oprea1_185678;SureCN1549479 |
| 分子量: | 309.3 |
| 分子式: | C18H15NO4 |
| SMILES: | COC1=CC=C(CN2C(C=CC=C3)=C3C(C(C(O)=O)=C2)=O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BQCA是高度选择性的M1mAChR变构调节剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Ma, L., Seager, M.A., Wittman, M., et al.Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiationProc. Natl. Acad. Sci. USA106(37),15950-15955(2009)
Shirey, J.K., Brady, A.E., Jones, P.J., et al.A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learningJ. Neurosci.29(45),14271-14286(2009)
Chambon, C., Jatzke, C., Wegener, N., et al.Using cholinergic M1 receptor positive allosteric modulators to improve memory via enhancement of brain cholinergic communicationEur. J. Pharmacol.697(1-3),73-80(2012)
Galloway, C.R., Lebois, E.P., Shagarabi, S., et al.Effects of selective activation of M1 and M4 muscarinic receptors on object recognition memory performance in ratsPharmacology93(1-2),57-64(2014)
