11β-Prostaglandin E2
Cat. No.:YN322496
CAS No. :38310-90-6
产品名称: | 11β-Prostaglandin E2 |
CAS No.: | 38310-90-6 |
Chemical Name: | 9-oxo-11β,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid |
Synonyms: | 11β-前列腺素E2; 11β-Dinoprostone; 11β-PGE2 |
分子量: | 352.5 |
分子式: | C20H32O5 |
SMILES: | O=C1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@@H](O)C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 11β-Prostaglandin E2 (11β-Dinoprostone) 是一种前列腺素衍生物,可抑制 [3H]PGE2与大鼠下丘脑膜的结合,Ki值为 53.3 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Dray, F., and Heaulme, M.Prostaglandins of the E series inhibit release of noradrenaline in rat hypothalamus by a mechanism unrelated to classical α2 adrenergic presynaptic inhibitionNeuropharmacology23,457-462(1984)
Raisz, L.G., and Woodiel, F.N.Effect of alterations in the cyclopentane ring on bone resorptive activity of prostaglandinProstaglandins37,229-235(1989)
Itoh, S., Lu, R., Bao, Y., et al.Structural determinants of substrates for the prostaglandin transporter PGTMol. Pharmacol.50,736-742(1996)