YE120
Cat. No.：YN322497
| 产品名称: | YE120 |
| CAS No.: | 383124-82-1 |
| Chemical Name: | 2-[3-cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]-propanedinitrile |
| Synonyms: | YE-120, YE120, YE 120 |
| 分子量: | 330.16768 |
| 分子式: | C16H9Cl2N3O |
| SMILES: | CC1=C(C#N)/C(OC1(C)C2=CC(Cl)=C(Cl)C=C2)=C(C#N)/C#N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | YE120 是一种有效的GPR35激动剂，其EC50为 32.5 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Deng, H., Hu, H., He, M., et al.Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonistsJ. Med. Chem.54(20),7385-7396(2011)
Tsukahara, T., Hamouda, N., Utsumi, D., et al.G protein-coupled receptor 35 contributes to mucosal repair in mice via migration of colonic epithelial cellsPharmacol. Res.123,27-39(2017)
