PSN 375963
Cat. No.:YN322499
CAS No. :388575-52-8
产品名称: | PSN 375963 |
CAS No.: | 388575-52-8 |
Chemical Name: | 4-[5-(4-butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridine |
Synonyms: | |
分子量: | 285.4 |
分子式: | C17H23N3O |
SMILES: | CCCCC1CCC(CC1)c1onc(n1)c1ccncc1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PSN 375963 是一种有效的GPR119激动剂,对人和小鼠的EC50分别为 8.4 和 7.9 μM。PSN 375963 显示出与内源性油酰乙醇酰胺 (OEA) 相似的效力。 |
IC50和靶点: | |
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In Vivo: | |
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Fu, J., Gaetani, S., Oveisi, F., et al.Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-αNature425(6953),90-93(2003)
Overton, H.A., Babbs, A.J., Doel, S.M., et al.Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agentsCell Metab.3(3),167-175(2006)