Pasireotide
Cat. No.：YN322501
| 产品名称: | Pasireotide |
| CAS No.: | 396091-73-9 |
| Chemical Name: | Cyclo[(2S)-2-phenylglycyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-tyrosyl-L-phenylalanyl-(4R)-4-[[[(2-aminoethyl)amino]carbonyl]oxy]-L-prolyl]; SOM 230; SOM 320; Signifor |
| Synonyms: | 帕瑞肽; SOM230 |
| 分子量: | 1047.206 |
| 分子式: | C58H66N10O9 |
| SMILES: | NCCCCC1NC(=O)C(CC2C3C=CC=CC=3NC=2)NC(=O)C(NC(=O)C2CC(OC(=O)NCCN)CN2C(=O)C(NC(=O)C(CC2C=CC(OCC3C=CC=CC=3)=CC=2)NC1=O)CC1C=CC=CC=1)C1C=CC=CC=1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pasireotide (SOM230) 是一种长效的环己肽生长激素抑制素类似物，可以提高生长抑素受体的激动剂活性，对sst1/2/3/4/5的pKi分别为 8.2/9.0/9.1/<7.0/9.9。Pasireotide 可以抑制 GH、IGF-I 和 ACTH 的分泌，可用于研究肢端肥大症和库欣病。Pasireotide 还具有抗分泌、抗增殖和促凋亡活性。 |
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| Solvent & Solubility: |
Petersenn, S., et al.: Endocrine, 57, 156 (2017)
