TC-O 9311
Cat. No.:YN322516
CAS No. :444932-31-4
产品名称: | TC-O 9311 |
CAS No.: | 444932-31-4 |
Chemical Name: | 3,5-dimethoxy-benzoic acid, 2-[(1-naphthalenylamino)carbonyl]hydrazide |
Synonyms: | |
分子量: | 365.4 |
分子式: | C20H19N3O4 |
SMILES: | COC1=CC(OC)=CC(C(NNC(NC2=CC=CC3=C2C=CC=C3)=O)=O)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | TC-O 9311 是一种有效的孤儿 G 蛋白偶联受体 139(GPR139)激动剂,EC50值为 39 nM。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Shi, F., Shen, J.K., Chen, D., et al.Discovery and SAR of a series of agonists at orphan G protein-coupled receptor 139ACS Med. Chem. Lett.2(4),303-306(2011)
Bayer Andersen, K., Leander Johansen, J., Hentzer, M., et al.Protection of primary dopaminergic midbrain neurons by GPR139 agonists supports different mechanisms of MPP+ and rotenone toxicityFront. Cell. Neurosci.10:164,(2016)