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TC-O 9311

Cat. No.:YN322516

  • CAS No. :444932-31-4

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    • 参考文献
    • 产品名称: TC-O 9311
      CAS No.: 444932-31-4
      Chemical Name: 3,5-dimethoxy-benzoic acid, 2-[(1-naphthalenylamino)carbonyl]hydrazide
      Synonyms:
      分子量:365.4
      分子式:C20H19N3O4
      SMILES:COC1=CC(OC)=CC(C(NNC(NC2=CC=CC3=C2C=CC=C3)=O)=O)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: TC-O 9311 是一种有效的孤儿 G 蛋白偶联受体 139(GPR139)激动剂,EC50值为 39 nM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Shi, F., Shen, J.K., Chen, D., et al.Discovery and SAR of a series of agonists at orphan G protein-coupled receptor 139ACS Med. Chem. Lett.2(4),303-306(2011)

      Bayer Andersen, K., Leander Johansen, J., Hentzer, M., et al.Protection of primary dopaminergic midbrain neurons by GPR139 agonists supports different mechanisms of MPP+ and rotenone toxicityFront. Cell. Neurosci.10:164,(2016)

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