Harmane
Cat. No.：YN380388
| 产品名称: | Harmane |
| CAS No.: | 486-84-0 |
| Chemical Name: | 1-methyl-9H-pyrido[3,4-b]indole |
| Synonyms: | 哈尔满碱 |
| 分子量: | 182.22128 |
| 分子式: | C12H10N2 |
| SMILES: | CC1=NC=CC2=C1NC3=CC=CC=C23 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Harmane，一种 β-咔啉生物碱 (BCA)，是有效的神经毒素，可引起严重的动作震颤和精神病学表现。Harmane 对 I1 咪唑啉受体 (I1-Imidazoline receptor,IC50=30 nM) 的选择性是对 α2-肾上腺素受体 (IC50=18 μM) 的 1000 倍。Harmane 还是有效和选择性的单胺氧化酶抑制剂 (对MAO A/B的IC50值分别为 0.5 μM 和 5 μM)。Harmane 具有致突变作用。 |
| IC50和靶点: | [{name:"hMAO-A:0.5 μM (IC50)"},{name: "MAO-B:5 μM (IC50)"},{name: "α2-adrenergic receptor:18 μM (IC50)"},{name: "I1-Imidazoline receptor:30 nM (IC50)"}] |
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| Solvent & Solubility: |
Blei, F., Dörner, S., Fricke, J., et al.Simultaneous production of psilocybin and a cocktail of β-carboline monoamine oxidase inhibitors in "magic" mushroomsChemistry26(3),729-734(2020)
