NESS 0327
Cat. No.:YN322532
产品名称: | NESS 0327 |
CAS No.: | 494844-07-4 |
Chemical Name: | 8-chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydro-N-1-piperidinyl-benzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide |
Synonyms: | NESS 0327;NESS0327 |
分子量: | 489.8 |
分子式: | C24H23Cl3N4O |
SMILES: | Clc1ccc2c(CCCc3c(nn(c23)c2ccc(Cl)cc2Cl)C(=O)NN2CCCCC2)c1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | NESS 0327 是一种大麻素cannabinoid拮抗剂,对大麻素CB1受体具有高选择性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Ruiu, S., Pinna, G.A., Marchese, G., et al.Synthesis and characterization of NESS 0327: A novel putative antagonist of the CB1 cannabinoid receptorJ. Pharmacol. Exp. Ther.306(1),363-370(2003)
Tambaro, S., Mongeau, R., Dessi, C., et al.Modulation of ATP-mediated contractions of the rat vas deferens through presynaptic cannabinoid receptorsEur. J. Pharmacol.525,150-153(2005)