LH21
Cat. No.：YN322535
| 产品名称: | LH21 |
| CAS No.: | 502486-89-7 |
| Chemical Name: | 1-(2,4-dichlorophenyl)-5-(4-methoxyphenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide |
| Synonyms: | |
| 分子量: | 459.4 |
| 分子式: | C23H24Cl2N4O2 |
| SMILES: | ClC1=CC=C(N2C(C3=CC=C(OC)C=C3)=C(C)C(C(NN4CCCCC4)=O)=N2)C(Cl)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NIDA-41020 是一种有效的选择性大麻素受体1 (CB1)拮抗剂，其Ki为 4.1 nM。NIDA-41020 被设计为一种潜在的放射性配体，用于正电子发射断层扫描 (PET)。 |
| IC50和靶点: | [{name:"CB1:4.1 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Katoch-Rouse, R., Pavlova, O.A., Caulder, T., et al.Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: Development of central cannabinoid receptor ligands with lower lipophilicityJ. Med. Chem.46(4),642-645(2003)
Donohue, S.R., Halldin, C., and Pike, V.W.Synthesis and structure-activity relationships (SARs) of 1,5-diarylpyrazole cannabinoid type-1 (CB1) receptor ligands for potential use in molecular imagingBioorg. Med. Chem.14(11),3712-3720(2006)
