Hyodeoxycholic acid-d
Cat. No.:YN322568
产品名称: | Hyodeoxycholic acid-d |
CAS No.: | 60320-05-0 |
Chemical Name: | (3α,5β,7α,12α)-3,12-dihydroxy-7-(sulfooxy)-cholan-24-oic acid |
Synonyms: | 7-Sulfocholic acid |
分子量: | 488.6 |
分子式: | C24H40O8S |
SMILES: | C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](OS(O)(=O)=O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@@]21C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Cholic acid 7-sulfate (7-Sulfocholic acid),一种 Cholic acid 的代谢物,是TGR5激动剂。Cholic acid 7-sulfate 可增加 Tgr5 表达并诱导GLP-1分泌。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Alnouti, Y.Bile acid sulfation: A pathway of bile acid elimination and detoxificationToxicol. Sci.108(2),225-246(2009)
Zhang, Y., and Klaassen, C.D.Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in miceJ. Lipid Res.51(11),3230-3242(2010)