MK-212 monohydrochloride
Cat. No.：YN380398
CAS No. ：61655-58-1
| 产品名称: | MK-212 monohydrochloride |
| CAS No.: | 61655-58-1 |
| Chemical Name: | 2-chloro-6-(1-piperazinyl)-pyrazine, monohydrochloride |
| Synonyms: | CPP monohydrochloride |
| 分子量: | 235.11324 |
| 分子式: | C8H11ClN4 • HCl |
| SMILES: | ClC1=CN=CC(N2CCNCC2)=N1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MK-212 (CPP) monohydrochloride 是一种中枢作用的5-HT1C/5-HT2激动剂。MK-212 monohydrochloride 可以刺激大脑皮层中的磷酸肌醇水解。 |
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Jensen, A.A., Plath, N., Pedersen, M.H.F., et al.Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: Novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive propertiesJ. Med. Chem.56(3),1211-1227(2013)
J.C., H., Lawton, C.L., and Blundell, J.E.The 5-HT2 receptor agonist MK-212 reduces food intake and increases resting but prevents the behavioural satiety sequencePharmacol. Biochem. Behav.56(1),41-46(1997)
Neisewander, J.L., and Acosta, J.I.Stimulation of 5-HT2C receptors attenuates cue and cocaine-primed reinstatement of cocaine-seeking behavior in ratsBehav. Pharmacol.18(8),791-800(2007)
