Carvedilol-d
Cat. No.：YN322580
| 产品名称: | Carvedilol-d |
| CAS No.: | 62929-91-3 |
| Chemical Name: | rel-8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-2(1H)-quinolinone, monohydrochloride |
| Synonyms: | 盐酸丙卡特罗 |
| 分子量: | 326.8182 |
| 分子式: | C16H22N2O3 • HCl |
| SMILES: | O=C1C=CC2=C([C@@H]([C@H](NC(C)C)CC)O)C=CC(O)=C2N1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Procaterol hydrochloride 是一种选择性的中效β2肾上腺素能受体激动剂，EC50为 12.9 µM。Procaterol hydrochloride 可以抑制体内外炎症。 |
| IC50和靶点: | |
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Marullo, S., Emorine, L.J., Strosberg, A.D., et al.Selective binding of ligands to β1, β2 or chimeric β1/β2-adrenergic receptors involves multiple subsitesEMBO J.9(5),1471-1476(1990)
Kikkawa, H., Naito, K., and Ikezawa, K.Tracheal relaxing effects and β2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissuesJpn. J. Pharmacol.57(2),175-185(1991)
Yoshizaki, S., Tanimura, K., Tamada, S., et al.Sympathomimetic amines having a carbostyril nucleusJ. Med. Chem.19(9),1138-1142(1976)
Mirza, Z.N., Tokuyama, K., Arakawa, H., et al.Inhaled procaterol inhibits histamine-induced airflow obstruction and microvascular leakage in guinea-pig airways with allergic inflammationClin. Exp. Allergy28(5),644-652(1998)
