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1-Oleoyl lysophosphatidic acid

Cat. No.:YN322593

  • CAS No. :65528-98-5

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: 1-Oleoyl lysophosphatidic acid
      CAS No.: 65528-98-5
      Chemical Name: 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid
      Synonyms:1-Oleoyl-sn-glycero-3-phosphate; 1-Oleoyl-LPA
      分子量:436.5
      分子式:C21H41O7P
      SMILES:CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) 是一种丰富的溶血磷脂酸种类,由于其对 LPA 受体 (LPA receptors) 的强亲和力,具有很高的生物活性。1-Oleoyl lysophosphatidic acid 在大多数实验室中常用作 LPA 受体激活的试剂。1-Oleoyl lysophosphatidic acid 可增加 SRE 驱动的 β-galactosidase 的活性。
      IC50和靶点:
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    • Moolenaar, W.H.LPA: A novel lipid mediator with diverse biological actionsTrends Cell Biol.4(6),213-219(1994)

      Noguchi, K., Ishii, S., and Shimizu, T.Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg familyJ. Biol. Chem.278(28),25600-25606(2003)

      Jalink, K., Hengeveld, T., Mulder, S., et al.Lysophosphatidic acid-induced Ca2+ mobilization in human A4431 cells: Structure-activity analysisBiochem. J.307,609-616(1995)

      van Corven, E.J., van Rijswijk, A., Jalink, K., et al.Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suraminBiochem. J.281,163-169(1992)

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