Ipratropium bromide hydrate
Cat. No.：YN322597
CAS No. ：66985-17-9
| 产品名称: | Ipratropium bromide hydrate |
| CAS No.: | 66985-17-9 |
| Chemical Name: | (3-endo,8-syn)-3-(3-Hydroxy-1-oxo-2-phenylpropyl)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane Bromode Monohydrate; Atropine Isopropyl Bromide; |
| Synonyms: | Sch 1000 bromide hydrate |
| 分子量: | 430.38 |
| 分子式: | C20H32BrNO4 |
| SMILES: | O.[Br-].CC(C)[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ipratropium bromide (Sch 1000) hydrate 是毒蕈碱的受体 (muscarinic receptor) 的拮抗剂，对 M1、M2 和 M3 受体的结合的IC50值分别为 2.9 nM、2 nM 和 1.7 nM。Ipratropium bromide hydrate 具有放松平滑肌的作用，可用于慢性阻塞性肺病 (COPD) 和哮喘等研究。 |
| IC50和靶点: | [{name:"mAChR1:2.9 nM (IC50)"},{name: "mAChR2:2 nM (IC50)"},{name: "mAChR3:1.7 nM (IC50)"}] |
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| Solvent & Solubility: |
Groeben, H., et al.: Anesthesiology, 85, 867 (1996), Haddad, et al.: Br. J. Pharmacol., 127, 413 (1999), Barnes, P. J., et al.: Chest, 117, 63S (2000),
