MNI137
Cat. No.:YN322612
CAS No. :6971-97-7
产品名称: | MNI137 |
CAS No.: | 6971-97-7 |
Chemical Name: | Benzaldehyde Azine; 3,3'-Dichlorobenzaldazine; 3,3'-Dichlorobenzylideneazine; NSC 67224; m-Chlorobenzaldehyde Azine |
Synonyms: | |
分子量: | 277.15 |
分子式: | C14H10Cl2N2 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | DCB (3,3'-dichlorobenzaldazine) 是代谢型谷氨酸受体5 (mGluR5)的中性变构调节剂。DCB 在 3,3'-二氟苯达嗪 (DFB) 的帮助下阻断 mGluRs (mGluR5) 的正变构调节。DCB 显示出 3,3'-二甲氧基苯扎嗪 (DMeOB) 的负调节作用。 |
IC50和靶点: | |
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Clinical Trial: | |
Solvent & Solubility: |
1. O’Brien, J. et al.: Mol Pharmacol. 2003 Sep
64(3):731-40. & 2. GarcÃa, O. et al.: J Neurosci Res. 2003 Dec 15
74(6):956-66.