Vorapaxar sulfate
Cat. No.：YN322614
CAS No. ：705260-08-8
| 产品名称: | Vorapaxar sulfate |
| CAS No.: | 705260-08-8 |
| Chemical Name: | N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-Fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]carbamic Acid Ethyl Ester Sulfate; |
| Synonyms: | SCH 530348 sulfate |
| 分子量: | 590.66 |
| 分子式: | C29H35FN2O8S |
| SMILES: | C(OCC)(=O)N[C@H]1CC[C@]([H])2[C@]([H])(C1)C[C@@]([H])1C(=O)O[C@@H](C)[C@]1([H])[C@@H]2/C=C/C1=NC=C(C2=CC=CC(F)=C2)C=C1.S(O)(O)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Vorapaxar sulfate (SCH 530348 sulfate)，抗血小板活性分子，是一种选择性、口服活性和竞争性的凝血酶受体蛋白酶激活受体(PAR-1)拮抗剂，Ki值为 8.1 nM。Vorapaxar sulfate剂量依赖性抑制凝血酶受体激活肽 (TRAP) 诱导的血小板聚集。 |
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| Solvent & Solubility: |
Boyle, J., et al.: Curr. Vasc. Pharmacol., 3, 63 (2005), Jennings, L., et al.: Expert. Opin. Drug Metab. Toxicol., 1, 727 (2005), Chackalamannil, S., et al.: J. Med. Chem., 49, 5389 (2006),
