Thielavin A
Cat. No.：YN322619
| 产品名称: | Thielavin A |
| CAS No.: | 71950-66-8 |
| Chemical Name: | 4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethyl-benzoic acid, 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester |
| Synonyms: | |
| 分子量: | 538.5 |
| 分子式: | C29H30O10 |
| SMILES: | CC1=C(O)C=C(C)C(C(OC2=C(C)C(C)=C(C(OC3=C(C)C(C)=C(C(O)=O)C(O)=C3C)=O)C(O)=C2C)=O)=C1O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Thielavin A 是一种由 Thielavia terricola 产生的前列腺素生物合成抑制剂。Thielavin A 特异性抑制花生四烯酸转化为前列腺素 H2。Thielavin A 在静脉注射或口服给药时没有抗炎活性。 |
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Kitahara, N., Haruyama, H., Hata, T., et al.The structures of thielavins A, B and C. Prostaglandin synthetase inhibitors from fungiJ. Antibiot. (Tokyo)36(5),599-600(1983)
Kitahara, N., Endo, A., Furuya, K., et al.Thielavin A and B, new inhibitors of prostaglandin biosynthesis produced by Thielavia terricolaJ. Antibiot. (Tokyo)34(12),1562-1568(1981)
Sakemi, S., Hirai, H., Ichiba, T., et al.Thielavins as glucose-6-phosphatase (G6Pase) inhibitors: Producing strain, fermentation, isolation, structural elucidation and biological activitiesJ. Antibiot. (Tokyo)55(11),941-951(2002)
Take, Y., Inouye, Y., and Nakamura, S.Comparative studies of the inhibitory properties of antibiotics on human immunodeficiency virus and avian myeloblastosis virus reverse transcriptases and cellular DNA polymerasesJ. Antibiot. (Tokyo)42(1),107-115(1989)
Rivera-Chávez, J., González-Andrade, M., González Mdel, C., et al.Thielavins A, J and K: α-Glucosidase inhibitors from MEXU 27095, an endophytic fungus from Hintonia latifloraPhytochemistry94,198-205(2013)
