Xamoterol hemifumarate
Cat. No.：YN322626
| 产品名称: | Xamoterol hemifumarate |
| CAS No.: | 73210-73-8 |
| Chemical Name: | N-[2-[[2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]-4-morpholinecarboxamide, (E)-2-butenedioate (2:1) |
| Synonyms: | Corwin hemifumarate; ICI 118587 hemifumarate |
| 分子量: | 397.4 |
| 分子式: | C16H25N3O5 • 1/2C4H4O4 |
| SMILES: | O=C(NCCNCC(O)COC1=CC=C(O)C=C1)N2CCOCC2.OC(/C=C/C(O)=O)=O.O=C(NCCNCC(O)COC3=CC=C(O)C=C3)N4CCOCC4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Xamoterol hemifumarate 是一种选择性强效的β1-肾上腺素受体激动剂。Xamoterol hemifumarate 具有研究心律失常的潜力。Xamoterol hemifumarate 具有研究 β1-肾上腺素能刺激与 IKr 之间关系的潜力。 |
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Willette, R.N., Aiyar, N., T.-L., Y., et al.In vitro and in vivo characterization of intrinsic sympathomimetic activity in normal and heart failure ratsJ. Pharmacol. Exp. Ther.289(1),48-53(1999)
Kowalski, M.T., Haworth, D., Lu, X., et al.Comparison of the effects of xamoterol and isoprenaline on rat cardiac β-adrenoceptors: Studies of function and regulationBr. J. Pharmacol.99(1),27-30(1990)
Nuttall, A., and Snow, H.M.The cardiovascular effects of ICI 118,587: A β1-adrenoceptor partial agonistBr. J. Pharmacol.77(2),381-388(1982)
