Remoxipride (hydrochloride)
Cat. No.：YN322627
| 产品名称: | Remoxipride (hydrochloride) |
| CAS No.: | 73220-03-8 |
| Chemical Name: | 3-bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2,6-dimethoxy-benzamide, monohydrochloride |
| Synonyms: | Remoxipride Hydrochloride (anhydrous); Remoxipride HCl; Roxiam; A 33547 hydrochloride; UNII-QS4S72U30K; QS4S72U30K; Remoxipride Hydrochloride Anhydrous ; Remoxipride Monohydrochloride; Remoxipride Monohydrochloride Monohydrate; Remoxipride |
| 分子量: | 407.73014 |
| 分子式: | C16H23BrN2O3 • HCl |
| SMILES: | BrC1=CC=C(OC)C(C(NC[C@H]2N(CC)CCC2)=O)=C1OC.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (S)-Remoxipride ((-)-Remoxipride) hydrochloride 是选择性的多巴胺D2-receptor拮抗剂，IC50值为 1.57 μM。(S)-Remoxipride hydrochloride 可以用于精神障碍的研究。 |
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Leysen, J.E., Janssen, P.M.F., Schotte, A., et al.Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: Role of 5HT2 receptorsPsychopharmacology (Berl)112(1 Suppl),S40-S54(1993)
Magnusson, O., Mohringe, B., Thorell, G., et al.Effects of the dopamine D2 selective receptor antagonist remoxipride on dopamine turnover in the rat brain after acute and repeated administrationPharmacol. Toxicol.60(5),368-373(1987)
Ögren, S.O., Hall, H., Kohler, C., et al.Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brainEur. J. Pharmacol.102(3-4),459-574(1984)
