AZD-5672
Cat. No.:YN322638
产品名称: | AZD-5672 |
CAS No.: | 780750-65-4 |
Chemical Name: | |
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分子量: | 632.78 |
分子式: | C32H38F2N2O5S2 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | AZD-5672 是一种口服有效的强效选择性CCR5拮抗剂 (IC50=0.32 nM)。AZD-5672 对hERG离子通道具有中等活性 (结合IC50=7.3 μM)。AZD5672是人P-gp的底物,抑制 P-gp 介导的地高辛转运 (IC50=32 μM)。AZD-5672 可用于类风湿性关节炎的研究。 |
IC50和靶点: | [{name:"CCR5:0.32 nM (IC50)"},{name: "hERG:7.3 μM (IC50)"},{name: "hP-gp:32 μM (IC50)"}] |
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Clinical Trial: | |
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