LP44 hydrochloride
Cat. No.:YN322647
CAS No. :824958-12-5
产品名称: | LP44 hydrochloride |
CAS No.: | 824958-12-5 |
Chemical Name: | 4-[2-(methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-1-piperazinehexanamide, monohydrochloride |
Synonyms: | LP-44; LP 44; LP44; compound 5 [PMID 17649988]. |
分子量: | 488.1 |
分子式: | C27H37N3OS • HCl |
SMILES: | O=C(CCCCCN1CCN(C2=C(SC)C=CC=C2)CC1)NC3CCCC4=CC=CC=C43.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | LP44 (hydrochloride) 是一种选择性5-HT7激动剂, 其Ki值为0.22 nM。LP44 (hydrochloride) 通过脑室内注射以剂量依赖性方式诱导低温效应。LP44 (hydrochloride) 通过腹腔给药不会引起显着的低温反应。 |
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Leopoldo, M., Berardi, F., Colabufo, N.A., et al.Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agentsJ. Med. Chem.47,6616-6624(2004)