TASP0376377
Cat. No.：YN322659
CAS No. ：847727-81-5
| 产品名称: | TASP0376377 |
| CAS No.: | 847727-81-5 |
| Chemical Name: | 4-[(1S)-1-[[[5-chloro-2-(3-fluorophenoxy)-3-pyridinyl]carbonyl]amino]ethyl]-benzoic acid |
| Synonyms: | AAT008 |
| 分子量: | 414.8 |
| 分子式: | C21H16ClFN2O4 |
| SMILES: | C[C@H](NC(C1=CC(Cl)=CN=C1OC2=CC=CC(F)=C2)=O)C3=CC=C(C(O)=O)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AAT-008 是一种有效、选择性、口服活性的前列腺素EP4受体拮抗剂，重组人 EP4 和重组大鼠 EP4 的Ki分别为 0.97 和 6.1 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Okumura, Y., Yamagishi, T., Nukui, S., et al.Discovery of AAT-008, a novel, potent, and selective prostaglandin EP4 receptor antagonistBioorg. Med. Chem. Lett.27(5),1186-1192(2017)
