DG-041
Cat. No.：YN322663
CAS No. ：861238-35-9
| 产品名称: | DG-041 |
| CAS No.: | 861238-35-9 |
| Chemical Name: | (2E)-3-[1-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-1H-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide |
| Synonyms: | |
| 分子量: | 592.32 |
| 分子式: | C23H15Cl4FN2O3S2 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | DG-041 是一种有效，高亲和力，选择性的EP3受体拮抗剂，在结合和 FLIPR 试验中，IC50分别为 4.6 nM 和 8.1 nM。DG-041 抑制PGE2促进血小板聚集。DG-041 可以穿过血脑屏障。 |
| IC50和靶点: | [{name:"EP3:4.6-8.1 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Heptinstall, S., et al.: Platelets, 19, 605 (2008)
Singh, J., et al.: ACS Chem. Biol., 4, 115 (2009)
Zegar, S., et al.: Org. Proc. Res. Dev., 11, 747 (2007)
