Methoxy-X04
Cat. No.:YN380412
CAS No. :863918-78-9
产品名称: | Methoxy-X04 |
CAS No.: | 863918-78-9 |
Chemical Name: | 4,4'-[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis-phenol |
Synonyms: | |
分子量: | 344.4 |
分子式: | C23H20O3 |
SMILES: | OC1=CC=C(/C=C/C2=CC=C(/C=C/C3=CC=C(O)C=C3)C(OC)=C2)C=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Methoxy-X04 是一种荧光染料,可以穿过血脑屏障,选择性地结合在致密中心淀粉样蛋白Aβ斑块中的β-折叠层。 |
IC50和靶点: | |
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Klunk, W.E., Backsai, B.J., Mathis, C.A., et al.Imaging Aβ plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative.J. Neuropathol. Exp. Neurol.61(9),797-805(2002)
Burgold, S., Bittner, T., Dorostkar, M.M., et al.In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeksActa. Neuropathol.121(3),327-335(2011)